This feature is only available for Devolutions Server, Microsoft Azure SQL, Microsoft SQL Server, and SQLite data sources.
Multifactor authentication (MFA) identifies users by at least two different components: something that the user knows (often a password) and something that the user possesses (e.g., a validation code sent to a mobile device). If one of the components is missing or supplied incorrectly, the user's identity is not established with sufficient certainty and access to the data source will remain blocked.
MFA is set at the data source level, except in Devolutions Server, where it is set on the user. Remote Desktop Manager supports Authenticator (TOTP), Yubikey, and Duo.
Consult Lost the MFA set on the data source in the the MFA has been lost.
Go to the section that corresponds to your data source type:
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In Remote Desktop Manager, go to the data source for which you want to configure the MFA.
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Go to File – My account settings and click on Data source MFA.

File – My account settings – Data source MFA -
In the Multifactor configuration window, click Change.

Change the multifactor configuration -
Select your MFA type in the drop-down list.

Multifactor authentication type -
Follow one of the links below depending on the choice made in the previous step:
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In Remote Desktop Manager, go to the data source for which you want to configure the MFA.
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Go to File – Data sources and click on the Edit data source button.

File – Data sources – Edit data source -
Next to the Multifactor option, click None.

Multifactor option -
In the Multifactor configuration window, click Change.

Change the multifactor configuration -
Select your MFA type in the drop-down list.

Multifactor authentication type -
Follow one of the links below depending on the choice made in the previous step:
In the Devolutions Hub Business web UI, head over to Administration – Authentication.
Toggle Enforce multi-factor verification on Devolutions Account. Doing so will force you to set up an MFA as well.
As written above, multifactor authentication is set on a per-user basis for Devolutions Server data sources. Here's how do to do:
Open the Devolutions Server web UI.
Go to Administration – Users, and Edit the user you wish to enforce MFA on.
In the Multi-factor tab, select Authenticator (TOTP). Changing the multifactor authentication of an administrator account requires entering its password.
Scan the QR code with your mobile app or use the key and account name to set up your account. Alternatively, you can check the Configure later by the user to leave those steps to the user.
Then, enter the code obtained by scanning the QR code.
Click Update to effectuate the changes for the user.
Go to the section that corresponds to you data source type:
In Remote Desktop Manager, go to the data source for which you want to configure the MFA.
Go to File – My account settings and click on Data source MFA.

In the Multifactor configuration window, click Change.

Select your MFA type in the drop-down list.

Follow one of the links below depending on the choice made in the previous step:
In Remote Desktop Manager, go to the data source for which you want to configure the MFA.
Go to File – Data sources and click on the Edit data source button.

Next to the Multifactor option, click None.

In the Multifactor configuration window, click Change.

Select your MFA type in the drop-down list.

Follow one of the links below depending on the choice made in the previous step:
In the Devolutions Hub Business web UI, head over to Administration – Authentication.
Toggle Enforce multi-factor verification on Devolutions Account. Doing so will force you to set up an MFA as well.
As written above, multifactor authentication is set on a per-user basis for Devolutions Server data sources. Here's how do to do:
Open the Devolutions Server web UI.
Go to Administration – Users, and Edit the user you wish to enforce MFA on.
In the Multi-factor tab, select Authenticator (TOTP). Changing the multifactor authentication of an administrator account requires entering its password.
Scan the QR code with your mobile app or use the key and account name to set up your account. Alternatively, you can check the Configure later by the user to leave those steps to the user.
Then, enter the code obtained by scanning the QR code.
Click Update to effectuate the changes for the user.